NotePeriplasmic Secretion of Native in Escherichia coli Ovalbuminwithout Signal CleavageJSBA
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چکیده
The biogenesis of secretory proteins in eukaryotes involves their translocation across the membrane of the endoplasmic reticulum. This process is evolutionarily related to protein translocation into the periplasm of prokaryotic cells.''2) In both, secretory proteins are generally synthesized as precursors with N-terminal signal sequences that are removed during translocation. As exceptions, however, ovalbumin]) and several other serpin proteins, such as plasminogen activator inhibitor type 2,4) squamous cell carci-
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تاریخ انتشار 2018